
The Substance: Albert Hofmann's LSD
“One drop changes everything.”
Synopsis
By coincidence rather than by design, the Swiss chemist Albert Hofmann makes a sensational discovery in the spring of 1943. He realizes that he is dealing with a powerful molecule that will have an impact that reaches far beyond the scientific world. THE SUBSTANCE is an investigation into our troubled relationship with LSD, told from its beginnings to today.
Credits
Related titles
No curated related titles yet. Use the edit affordance to add "More from this director", "Same franchise", or "Adaptation source material" entries — every change goes through the wiki review queue.
How many hands made this film
The scale of the collaboration
Principal cast & crew: 17
These are the principals we have on file — the full crew ran to the hundreds. Every film this size was made by far more hands than any credits list ever names.
Why a floor?
This is a minimum, not a total. We only count the credits we’ve captured so far, and coverage is uneven — a blockbuster might show a few hundred names while another of the same size shows a couple dozen. The real crews all ran into the thousands. The number here only grows as full credits are enriched — so we frame it as a floor, never a headcount.
Craft leads on file
Edited by Stefan KalinShot by Pio CorradiScored by Marcel Vaid
Also known as
- The Substance – Albert Hofmanns LSDde
- La sostanza - Storia dell'LSDit
Community tags
Be the first to tag this page — tags appear right away. Try a theme, capability, or subject (e.g. WWII, heist, slow burn, time travel, A24).
Help complete this page
We’re missing mpaa rating, logline. Sign in to add what you know.
Cast & Crew
17 unique people credited
Top billed cast
Trevor J Roling
as narrator in English version
Hanspeter Muller
as narrator in German version
Mario Scarabelli
as narrator in Italian version
Albert Hofmann
as Self
Stanislav Grof
as Self - psychiatrist
Martin A Lee
as Self - author
James S Ketchum
as Self - U.S. Army Colonel (Retired), Medical Corps
Franz X Vollenweider
as Self - neuroscientist, University of Zürich
Ken Kesey
as Self
Carolyn Garcia
as Self - Merry Pranksters
Directors
1Writers
1Producers
2Other crew
4Parents Guide
AI Personalities
Advisory Bot AI
I keep the family-safety picture honest — community advisories, AI-moderated, summarized without spin.
Ratings & reviews
We’re attempting to crowdsource this data.
Please submit below if you know where it’s available in your region — accurate confirmations help everyone find what they’re looking for.
Where to watch
Not currently streaming on any platform we track.
Gallery
Add imageNo community images for The Substance: Albert Hofmann's LSD yet
Add a still, a storyboard, or concept art — every image gets its own page where members can discuss it.
Trailers
No trailers logged for The Substance: Albert Hofmann's LSD yet — add the first one below.
Spot a trailer we’re missing?
Add a trailer from any film, show, or game.
Media & Uploads
Scripts, set photos, storyboards, score sketches — community-curated reference material for film students and industry professionals.
Did you or a loved one work on The Substance: Albert Hofmann's LSD?
Every stage matters — pitch decks and treatments from development, location scouts and table-reads from pre-production, set photos and crew anecdotes from production, edit-bay notes from post, and press kits, festival memories, or marketing ephemera from distribution. Any moment that didn't make the press tour, any document or photograph that's been sitting in a box — please share it so it's not lost to time.
We particularly welcome contributions from writers, producers, cast, crew, festival programmers, distributors, marketing teams, their families, and anyone who was there at any stage.
Sign in to contribute scripts, stills, photos, or behind-the-scenes stories.
Be the first to share something on The Substance: Albert Hofmann's LSD.
Scripts, scans, photos, score sketches — anything that helps another reader study this work.
Memorable quotes
Browse all →No quotes logged for The Substance: Albert Hofmann's LSD yet — add the first memorable line below.
Got a quote we’re missing?
Submit a line from any film, show, or game.
The conversation
Loading the conversation…
Comments (0)
on The Substance: Albert Hofmann's LSDNo comments yet. Be the first to share what you think.
Edit history
Loading edit history…
