MacGyver

Mac and the team go undercover at an upscale hotel that serves as a hub for international criminals in order to locate a woman with key information about Codex. Their mission becomes more complicated when they discover that their target has undergone a complete transformation, including a new identity and appearance.

After Taylor's former protégé is killed while trying to prevent the theft of a bio-weapon, Mac and the team work to recover it before it can be sold to a terrorist group, allowing Desi to carry out a major heist.

Russ is kidnapped, prompting Mac and the team to free a reformed, once-violent criminal from prison to aid in the search. Meanwhile, Mac and Desi face personal tensions as they evade capture.

During Mac's meeting with Desi's parents, an unexpected complication arises when her brother gets into trouble and requires immediate assistance. At the same time, Russ and Matty are forced to seek help from a former adversary after a promising recruit is kidnapped.

Mac and the team are led by a mysterious postcard to investigate a case left unresolved by a deceased colleague, aiming to provide closure and achieve justice.

During the first stay-at-home order of the COVID-19 pandemic, Mac, Bozer, and Riley attempt to intervene in a crime at a neighbor's house while under quarantine. At the same time, Russ finds his romantic relationship with his partner becoming more serious as they spend extended time together in isolation.

Mac and a friend are working on an experimental cancer treatment, but their secret research is exposed when their lab is broken into, leading to the kidnapping of Mac's partner and the stolen formula being used to develop a dangerous nerve agent.

Mac and the team investigate a deadly illness affecting Ian Cain and his embassy staff, while Taylor and Bozer collaborate with Jerry Ortega to penetrate a Codex cell.

Mac and his team are unable to prevent sensitive Department of Defense intelligence from falling into the hands of the antagonist group Codex. In response, Mac takes matters into his own hands by constructing his own equipment to scale a vertical cliff and intercept the data before it can be transmitted.

During a mission to track a Codex lead, Mac and the team discover that Murdoc has been hacking their communications and secretly recording them for months. They learn that Murdoc is now working with Andrews in a plot to kill thousands and reveal the hidden secrets of every Phoenix member. Mac and the team must act quickly to stop the escalating threat.

Mac and Riley travel abroad in an effort to prevent a political crisis, but they come across a dangerous new form of microscopic technology that puts them in jeopardy.

Mac, Desi, and Russ go undercover at a high-profile Indian royal wedding to protect a princess whose political views have made her a target. At the same time, Russ meets Sophia at the event, Bozer becomes suspicious of Riley's possible hacking, and Matty follows a lead to uncover the truth about Mac and Riley's nano-trackers.

Mac and the team investigate Italian car culture in an effort to track down a fugitive crime boss. Meanwhile, the boss begins to experience a loss of motor control in his hands and turns to Desi for help. Mac and Desi start living together, and Riley reveals to Russ the existence of her covert team of hackers.

Mac and Desi join Bozer in his hometown following the sudden death of his aunt, where they grow suspicious of foul play due to her ongoing efforts to expose tainted water in the city. At the same time, Riley, Matty, and Russ continue their investigation by pursuing new leads related to nano-trackers.

Mac and Riley awaken in a cornfield with no memory of the previous 24 hours and must uncover the truth behind their disappearance while dealing with mysterious nanotrackers embedded in their bodies.