Episode 15— O Brother, Where Art Thou?
Aired March 17, 2019 · 42 min

Synopsis
Lex Luthor, temporarily released from prison due to health issues, approaches his sister Lena for assistance in finding a cure, prompting her to question his true intentions. As tensions rise between family loyalty and suspicion, Supergirl and J'onn confront Manchester Black, while James's sister Kelly arrives in National City.
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