Perception

Neuroscience professor Daniel Pierce is asked by FBI Agent Kate Moretti, his former student, to assist in an investigation into the death of a pharmaceutical executive. As they work together, Daniel's struggles with schizophrenia and the accompanying hallucinations threaten to complicate the case.

Pierce assists in the investigation of a murdered mail-order bride, with a surprising twist when the main suspect is found to have a rare medical condition. Meanwhile, Moretti becomes interested in a charming new professor.

Pierce and Moretti investigate as a serial killer from 1986 resumes their crimes, gaining a lead when they discover one of the victims is still alive. Moretti seeks guidance from her father, who was involved in the original investigation, and Pamela Reed and Armin Shimerman appear in supporting roles as the victim's mother and psychologist, respectively.

Pierce investigates a coded message found in a newspaper, which may be linked to a murder, while racing against time to prevent another potential victim.

A young man in a cult claims to hear God's voice, prompting Pierce to investigate whether it's divine or a dangerous medical condition. Meanwhile, Pierce and Moretti examine whether his death is connected to his drug history or his involvement with a potentially fraudulent organization, with an IRS agent probing the group's finances. Pierce also receives an award from the university for his research.

Pierce assists the FBI in investigating a therapist's murder, while Moretti grows closer to Professor Hathaway. Meanwhile, Dean Haley enlists Pierce to lure the widow of a wealthy alumnus into funding a new building.

Pierce is forced to confront personal issues while working on a case involving a man with schizophrenia. At the same time, Moretti attempts to prove herself to her new FBI supervisor. Tom Sizemore and Edward Furlong appear as a high-ranking Irish mobster and a possibly involved aspiring tough guy, respectively.

Moretti and Pierce investigate the murder of a college student in her dorm room, leading Pierce to engage personally with several of his students and confront unresolved issues from his past. As the case unfolds, Moretti begins to reassess her relationship with Dr. Hathaway.

A student approaches Pierce with information suggesting a conspiracy to conceal the murder of a U.S. Senator, drawing him into a complex investigation.

Moretti begins to consider the possibility that Pierce's conspiracy theory has some validity, while Pierce is compelled by his new doctor to confront the reality of Natalie's situation.

FBI Agent Kate Moretti enlists Dr. Daniel Pierce to assess the mental state of a man on trial for murder. Pierce's evaluation raises doubts about the defendant's identity over time, complicating the case. At the same time, Moretti is surprised to find that the prosecutor is her soon-to-be-ex-husband, Donnie Ryan.

Pierce and Moretti investigate a woman's claim that aliens have taken her husband, only to uncover a surprising truth. At the same time, Pierce struggles to balance his feelings for his real girlfriend, Caroline, and his lingering attachment to his imaginary girlfriend, Natalie.

Pierce believes a string of unusual public murders is linked to the psychological concept of inattentional blindness, despite Donnie's skepticism. As they race to uncover the killer's pattern, Pierce devises a method to test his theory and prevent further attacks.

Pierce is invited to assist a prominent environmental activist investigating a series of unexplained neurological symptoms in a group of young girls, only to uncover a troubling underlying cause. At the same time, Moretti challenges Pierce's decision to take the case without consulting her.

Pierce and Morretti enter a virtual reality world to investigate the murder of Kurt Simpson, a frequent player of the online game Caleidoscope. As Pierce navigates the digital environment using an avatar, he begins to have difficulty distinguishing between the virtual world and reality.

Pierce teams up with Donnie to investigate a brain device meant to control tremors, which proves to have a dangerous defect that leads to a murder investigation. Their partnership faces challenges as the case grows more complex. Meanwhile, Lewicki gains insight from a personal experience in relationships.

Detective Moretti investigates a 1992 hit-and-run murder after receiving a deathbed confession, enlisting Pierce to assess the informant's credibility. The case takes an unexpected turn when the suspect's doctor reports the man's tumor has inexplicably vanished. As they probe further, Moretti and Pierce uncover a series of suspicious deaths linked to the original crime.

Pierce investigates a stabbing that occurs at a psychiatric hospital, uncovering troubling clues that suggest the facility may be hiding dangerous secrets. As the investigation unfolds, the hospital's staff and patients become increasingly suspect.

Donnie assists a war veteran dealing with a neurological condition, while Pierce encounters a former romantic partner.

Moretti is charged with criminal offenses after acting independently on a high-risk case, prompting Pierce and Donnie to work to exonerate her.

Pierce defends an autistic teenager being questioned in a murder investigation, while Dean Haley works to recruit a neuroscience prodigy to attend CLMU.

Lewicki's estranged brother unexpectedly arrives, complicating his current situation. Meanwhile, Kenny becomes the prime suspect in a murder investigation, and Lewicki receives a proposition that casts doubt on Pierce's allegiance.

Pierce investigates a rumor that the CIA is carrying out assassinations of American citizens, while dealing with the murder of a close friend. Meanwhile, Moretti works on addressing her personal struggles with trust.

Pierce faces accusations of stalking his ex-girlfriend, Caroline Newsome, leading to concerns about his mental health and job security. As the situation intensifies, Moretti teams up with a Canadian inspector to uncover the identity of the real stalker.

Dr. Daniel Pierce's idealized life in Paris is disrupted when he is recruited by the FBI to assist in a high-stakes international investigation. At the same time, his assistant Max Lewicki and Dean Paul Haley work to convince Pierce to return to Chicago.

A prosecutor dies unexpectedly in court, prompting Pierce and Moretti to investigate his death. At the same time, Moretti and Donnie begin considering the direction of their lives moving forward.

A young boy with a developmental disorder becomes a hostage during a bank robbery, prompting Moretti to involve Pierce in an interview to extract crucial information. As the perpetrators are captured, the detectives uncover that the crime is tied to a deeper, more complex issue beyond financial gain. At the same time, Pierce's estranged father, James, unexpectedly visits him.

Moretti asks Pierce to evaluate Elena Douglas, a murder suspect who claims to be possessed by the Devil. At the same time, challenges arise in Donnie and Moretti's wedding preparations.

Moretti and Pierce investigate the death of brilliant neuroscientist Landon Jennings, focusing on how the killer accessed his supposedly secure study. Meanwhile, Lewicki deals with increased responsibilities when Pierce's father, James, moves in with the team.

Moretti investigates the disappearance of an infant and uncovers an unusual and disturbing truth. As Pierce and Moretti delve into a connected murder case, they begin to suspect another child may be in danger. Meanwhile, Moretti and Donnie discuss their future, with Donnie considering a move to the suburbs.

Pierce becomes convinced that a gallery owner's death during a video installation was murder, not a seizure, and teams up with Moretti to investigate, drawing them into a high-profile art heist. As the case unfolds, Pierce is compelled to reassess his personal connection with Natalie.

Pierce is drawn back into a long-unsolved case when a deceased missing FBI agent is found, revealing that the killer remains at large. Despite his therapist's concerns about worsening his mental health, Pierce reluctantly agrees to assist Moretti in the investigation.

Donnie and Moretti become involved in a sniper attack at the Federal Building, prompting Pierce to investigate the shooter's vulnerability to Extreme Low Frequency waves. They travel to a remote area in Virginia known as the Quiet Zone, believing the shooter is hiding there. At the same time, Donnie is pursued by a charismatic woman who encourages him to consider a political career.

Donnie calls Pierce for assistance after getting into a difficult situation, and as the evidence against him mounts, Pierce and Moretti face their own uncertainties while trying to clear his name. Meanwhile, Pierce deals with the aftermath of his father's violent outburst at an assisted living facility.

Dr. Daniel Pierce faces a life-threatening injury, forcing his father and a close friend to consider a dangerous surgical option. As Pierce recovers, he begins to doubt the reality of his perceptions.

Agent Kate Moretti infiltrates an animal rights organization to uncover potential criminal activity, while Pierce contemplates confessing something important to her.

Pierce and Moretti investigate the murders of a Bangladeshi diplomat and a Chicago journalist, leading them to an international conspiracy. Meanwhile, Moretti deals with the stress of planning her upcoming wedding.

Pierce investigates the murder of a student and works to clear the victim's boyfriend while dealing with personal emotions as Kate and Donnie approach their wedding.

Pierce and Donnie embark on a search for Moretti, who vanishes on her wedding day. They discover she has been taken by a dangerous figure from Pierce's past. With time running out, the two must confront the threat to rescue her.